Wednesday, January 30, 2013

Smelling a Profit

(For fun, let's see if you can count the number of time the word "shit" or a reference to "shit" is used in this post. The answer is at the, uh, bottom.)

I'm going to be a rich man. One of my crack research assistants brought to my attention that doctors are treating bowel infections with fecal transplants. And as full of shit as I am, I can't help but smell an opportunity to squeeze out a little profit.

A drug resistant strain of bacteria known as Clostridium difficile (C. difficile) is causing more frequent and severe intestinal infections in patients being treated with antibiotics for various other maladies. The antibiotics treating the illnesses are also killing good bacteria that reside in the intestines. This collateral damage allows the C. difficile bacteria to attack the patient's digestive system, often causing severe diarrhea and bowel inflamation. This is according to the Mayo Clinic, and how can you doubt any report on intestinal problems when Mayo is involved?

Doctors have found no effective standard therapy to combat this bacteria, so some have opted to try a therapy that is "decidedly non-standard," which is an understatement. They are attempting to restore the patient's intestinal deficiency of good bacteria with microbes excreted by healthy patients. It's called "intestinal microbiome transplantation" - fecal transplants - and the success rate of this bacteriotherapy during studies is encouraging. Basically, doctors take a healthy shit from one person and put it into another. The microbes don't attack the enemy bacteria directly. What they do do is re-establish normal levels of healthy bacteria and allow the body to excrete natural healing defenses. And so far, there are no major side effects with this treatment other than diarrhea, constipation and burping. Burping? I don't know about you, but I can't recall anything that tasted better the second time coming up.

Everyone who donates gets
this neat pin!
So where's the profit in all of this for me? Donor feces. Why not? People who sell their blood can make $200-400 a month. Qualified sperm donors can make $200 a week during a six-month contract. I'm not talking about turning myself into a human soft-serve machine, but a few bucks to fill a Dixie cup every now and then is nothing to turn up your nose at. Of course, there is an element of timing involved with a donation such as this. It's not like a needle in the vein or leafing through a Playboy magazine.


Fecal Run 2013
Run like you gotta go, and
"Give a shit to save a life"

And it's not only about donating. Education is important, too. Events could be held to raise awareness and promote the fight against C. difficile. At fairs and festivals, set up informational kiosks shaped like outhouses. Better yet, use actual porta-potties! Sell brown, rubber "Giveashit" wristbands. Start a Givestrong foundation. Have a marathon to raise funds. The opportunities are endless, so to speak. Let's grease up that good ol' American marketing machine and polish up that golden turd to fund a cure.




So say "No!" to Jamie Lee Curtis and put down that yogurt. Because there's only one true source of natural probiotics!




(Answers: I got 31 - crack, bowel, fecal, shit, squeeze out, diarrhea, bowel, excretes, fecal, shit, do do, excrete, diarrhea, constipation, shit, feces, soft-serve, this*, outhouse, porta-potties, Giveashit, Givestrong, turd, & natural probiotics. In photos: shit, fecal, shit, ass, crappy, fecal, & shit. If you find others, you must justify them to me with the understanding that I will ultimately tell you you're full of shit.)

* "this" used in the context "such as this" is not only a direct reference to shit, it uses the same four letters.

Saturday, January 5, 2013

Going Over the Fiscal Waterfall in a Pork Barrel

Well, it's nice to be back. For those who didn't know, Grainiums was on hiatus. And while this moment in a blog post seems a little early for a parenthetical aside, we're going to have one.

(Hiatus is a Latin word translated as being a gap or interruption in continuity. It is derived from the past participle "hiare," meaning "to gape." To gape is defined as "to stare wonderingly or stupidly, often with the mouth open.")

That pretty much sums up what I've been doing for the past several weeks. But I wiped away the drool oozing from the corners of my mouth and set myself back to the ol' grindstone. Looking back at all of the events that occurred during the hiatus, nothing screamed "stare stupidly" more than the government's handling of the country's financial woes.

The United States was facing a two-headed monster on January 1 - tax increases and budget cuts. Fortunately with a deadline in effect, it meant our legislative bodies would burn the midnight oil to come up with a solution. At least I assumed the government was burning a petroleum product because the price of gas went up during this period. Facing public backlash and battling through partisan devisiveness, our elected representatives, in the tried and true, American get-to-it attitude, got half the job done. They eliminated the tax increases. But what about the budget cuts? This is going to be a tough one for them as there are lots of marquee funding choices on the chopping block. Social Security, Medicare, unemployment insurance, education. Hard to find things to cut from the budget, although it shouldn't be that difficult to at least find a starting point...

College humor - Punking a rattlesnake
with a fake squirrel.
The U.S. government gave two California academic institutions - San Diego State University, and the University of California, Davis - $325,000 to develop a robotic squirrel to help researchers at the schools study "the nuances between predator and prey" of the California ground squirrel and rattlesnakes. The robosquirrel, when placed in the proper environment and confronted by a real rattlesnake, is designed to wag its tail back and forth to simulate what a real squirrel would do in a similar situation.

(Spoiler Alert: That's all it was built to do.)

And that's all it did, because apparently that's what squirrels will do when threatened by a viper. Okay, that and it seems that real squirrels also have the speed and agility to dodge a rattlesnake strike, animated behavior that I guess doesn't quite fit in a $325K budget. So if the rattlesnake struck at the robotic squirrel, the chances are relatively high a bite would occur. However, the robosquirrel shares one other characteristic with a real squirrel besides a wagging tail: both have immunity to the effects of rattlesnake venom. This would be like me getting a government grant to buy you a bag of marshmallows to throw at me, but instead of me it's a cardboard cutout that looks like me. There's also no mouth, but there's a speaker where my mouth was so you can hear me warn you not to throw the marshmallows at me. And either a) you're so stupid you don't throw one, or b) you throw one and it hits the fake me because the fake me can't move, and it doesn't hurt.

The ground squirrel is not the only member of nature's crash-test dummy army. There is a robot lizard that does territorially-defensive push-ups, a robot female sage grouse that uses a spycam to collect data on male sage grouse's courtship behavior, and the fake cockroach soaked in pheromones to study cockroach peer pressure. Public funding for cockroaches...wearing musk.

I'm alright, nobody worry 'bout me.
Why you gotta give me a fight, why
don't you let me be.
Interesting ideas to kick around the campus coffee shop, but increasing our financial debt $325,000 for a study using a taxidermy squirrel that only wags its tail? By comparison, the gopher used in the movie Caddyshack - the one used to generate behavioral "nuances" between a rodent and a golf course groundskeeper - was also relatively cheap to build and operate, but at least that little fucker could dance...and to the tune of almost $40 million at the box office! So in essence, we don't need government funding directed toward post graduate work on rodents adding to our fiscal deficit. We need government funding directed toward film comedies with dancing rodents turning a profit! Watching a flash mob of dancing hamsters won't completely cure the country's debt woes, but it'll help us laugh while we pay it down.

SDSU defended the grant in part by pointing out the components to make the squirrel only cost a few hundred dollars. The rest of the $324,000 and change went to fund the 4 graduate students and 30 undergrad students participating in the project because, you know, we can't expect college students or their parents to pay for tuition, and hobbies aren't covered through student loans. Not that all scientific studies don't deserve government subsidies. I think discovering how diseases are transmitted between species is very important because that kind of knowledge has a practical application to humans. However, I've come across a few rattlers in my travels, and the last thing I think I'd do is "drop trou" and shake my ass hoping to keep them at bay.

And what of university officials and professors claims that a study of this nature has helped in understanding human behavior? Judging by public disbelief and outrage generated by their government funded shopping spree at Radio Shack...success!